Dr. Marie-Laure Yaspo did her postdoctoral research at the Imperial Cancer research Fund (London, UK). Since 1996 she has been a research group leader at the Max Planck Institute for Molecular Genetics (MPIMG, Berlin). She is currently head of the Otto Warburg Laboratory “Gene Regulation and Systems Biology of Cancer’ at the MPIMG. M-L Yaspo coordinated the International Consortium for mapping and sequencing Human chromosome 21 within the Human Genome Project. She participates in the International Cancer Genome consortium (ICGC early-onset prostate cancer and IGCG pediatric brain tumors) and the European Blueprint project.